Method of separating and purifying berberine alkaloid

Abstract

PURPOSE: To obtain in high purity berberine alkaloid, by treating tissue piece or cell of a plant with a specific alcohol to give an extracted solution, adding a specific salt exchanger to the solution to precipitate berberine alkaloid as a salt and separating berberine alkaloid. CONSTITUTION: Tissue piece of cell containing berberine alkaloid is treated with 2W4C aliphatic alcohol, the prepared extracted solution is incorporated with a salt exchanger containing chlorine ion and/or nitrate ion to precipitate berberine alkaloid as a salt, which is separated. COPYRIGHT: (C)1987,JPO&Japio

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    WO-0226244-A3August 28, 2003Next Pharmaceuticals IncCompositions et methodes d'utilisation d'extraits de plantes de la famille rutaceae